Staff Profile

Education

• BSc Biomedical Sciences (Hons) 2:1 - Newcastle University
• MRes Immunobiology Distinction - Newcastle University
• PhD in Mechanical Engineering - Newcastle University

Current research

After completing a PhD in Mechanical Engineering focussing on tissue inflammatory and osteolytic responses to materials used for orthopaedic joint replacement, Shannon is now a post-doctoral Research Associate in the Newcastle University Translational and Clinical Research Institute. The current ongoing research forms part of a wider Tissue and Explant Analysis of Medical Implant Failure (TEAM) study which involves the investigation of tissue responses in patients undergoing removal of failed implants. Shannon currently works on understanding the role of the immune system in the failure of urogynaecological meshes used for the treatment of stress urinary incontinence and pelvic organ prolapse using transcriptomic and spatial proteomic techniques. As part of the TEAM study, Shannon is also investigating inflammatory responses in the synovium of patients with failed joint replacements.

• Articles

  • Jamieson S, Hyde P, Card P, Deehan D, Kirby J, Tyson-Capper A. Poly-ether-ether-ketone wear particles induce a pro-inflammatory phenotype in a human monocytic cell line. Frontiers in Bioengineering and Biotechnology 2025, 13, 1507248.
  • Jamieson S, Mawdesley A, Deehan D, Kirby J, Holland j, Tyson-Capper A. Inflammatory responses to metal oxide ceramic nanopowders. Scientific Reports 2021, 11, 10531.

• Conference Proceedings (inc. Abstracts)

  • Jamieson S, Mawdesley A, Hyde P, Kirby J, Tyson-Capper A. Activation of Osteoblasts by Cobalt-Chromium Occurs Via a TLR4-Mediated Pathway. In: The International Combined Orthopaedic Research Societies (ICORS), World Congress of Orthopaedic Research. 2022, Edinburgh, Scotland: British Editorial Society of Bone and Joint Surgery.
  • Jamieson S, Tyson-Capper A, Hyde P, Kirby J. Understanding the immunobiology of orthopaedic biomaterials. In: The 29th Annual Meeting of the European Orthopaedic Research Society (EORS). 2021, Rome, Italy: The Bone & Joint Journal.
  • Anjum S, Jamieson S, Deehan D, Kirby J, Tyson-Capper A. The effect of simvastatin on cobalt-mediated inflammatory cytokine expression. In: The 29th Annual Meeting of the European Orthopaedic Research Society. 2021, Rome, Italy.

• Review

  • Jamieson S, Anjum S, Kirby J, Tyson-Capper A. Ceramic Biomaterials: what are their biological implications?. Bioengineering & Biosciences 2021, 4(4).